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α rad51c antibody 2h11 6  (Novus Biologicals)


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    Structured Review

    Novus Biologicals α rad51c antibody 2h11 6
    α Rad51c Antibody 2h11 6, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 94/100, based on 19 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rad51c/Rad51C+Antibody+(2H11%2F6)+-+BSA+Free/pm42020761-521-101-105
    Average 94 stars, based on 19 article reviews
    α rad51c antibody 2h11 6 - by Bioz Stars, 2026-09
    94/100 stars

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    Related Articles

    Western Blot:

    Article Title: MUS81 nuclease activity is essential for replication stress tolerance and chromosome segregation in BRCA2-deficient cells
    Article Snippet: .. The following antibodies were used for immunoblotting: mouse monoclonal antibodies raised against BRCA1 (1:2,000, OP92, Calbiochem), BRCA2 (1:2,000, OP95, Calbiochem), GAPDH (1:30,000, 6C5, Novus Biologicals), histone H3 (1:1,000, 865R2, Invitrogen), MUS81 (1:1,000, MTA30 2G10/3, Abcam), POLD3 (1:500, 3E2, Abnova), RAD51C (1:1,000, 2H11/6, Novus Biologicals), SLX4 (a gift from Professor John Rouse, University of Dundee) and α-tubulin (1:15,000, TAT1, Cancer Research UK Monoclonal Antibody Service). .. Rabbit polyclonal antibodies raised against phosphorylated histone H3 Ser10 (1:1,000, Abcam), RAD51 (1:2,000, H92, Santa Cruz) and SMC1 (1:4,000, BL308, Bethyl Laboratories).

    Article Title: Discovery of MFH290: A Potent and Highly Selective Covalent Inhibitor for Cyclin-Dependent Kinase 12/13.
    Article Snippet: Genetic depletion of cyclin-dependent kinase 12 (CDK12) or selective inhibition of an analog-sensitive CDK12 reduces DNA damage repair gene expression, but selective inhibition of endogenous CDK12 is difficult.. Here, we report the development of MFH290, a novel cysteine (Cys)-directed covalent inhibitor of CDK12/13.. MFH290 forms a covalent bond with Cys-1039 of CDK12, exhibits excellent kinome selectivity, inhibits the phosphorylation of serine-2 in the C-terminal domain (CTD) of RNA-polymerase II (Pol II) and reduces the expression of key DNA damage repair genes.

    Article Title: BCDX2-CX3 and DX2-CX3 complexes assemble and stabilize RAD51 filaments.
    Article Snippet: 16 17 The repair of DNA double-strand breaks by homologous recombination (HR) is essential for 18 genomic integrity, and its dysregulation is a hallmark of cancer.. Central to HR is the RAD51 19 recombinase, whose assembly into a nucleoprotein filament is governed by five RAD51 paralogs 20 (RAD51B, RAD51C, RAD51D, XRCC2, XRCC3).. Mutations in any of these proteins predispose 21 individuals to multiple cancers or genetic disorders.

    Bioprocessing:

    Article Title: MUS81 nuclease activity is essential for replication stress tolerance and chromosome segregation in BRCA2-deficient cells
    Article Snippet: .. The following antibodies were used for immunoblotting: mouse monoclonal antibodies raised against BRCA1 (1:2,000, OP92, Calbiochem), BRCA2 (1:2,000, OP95, Calbiochem), GAPDH (1:30,000, 6C5, Novus Biologicals), histone H3 (1:1,000, 865R2, Invitrogen), MUS81 (1:1,000, MTA30 2G10/3, Abcam), POLD3 (1:500, 3E2, Abnova), RAD51C (1:1,000, 2H11/6, Novus Biologicals), SLX4 (a gift from Professor John Rouse, University of Dundee) and α-tubulin (1:15,000, TAT1, Cancer Research UK Monoclonal Antibody Service). .. Rabbit polyclonal antibodies raised against phosphorylated histone H3 Ser10 (1:1,000, Abcam), RAD51 (1:2,000, H92, Santa Cruz) and SMC1 (1:4,000, BL308, Bethyl Laboratories).

    Article Title: Cellular Redistribution of Rad51 in Response to DNA Damage
    Article Snippet: Protease inhibitor tablets (Complete, with and without EDTA) were obtained from Roche Applied Sciences. .. Antibodies—The primary antibodies used were mouse monoclonal antibodies against Rad51 (clone 3C10, Upstate), Rad51B (ab3637, Abcam), Rad51C (NB 100-177, Novus), Rad51D (sc-53432, Santa Cruz Biotechnology), Xrcc2 (ab20253, Abcam), and Xrcc3 (NB 100-180D1, Novus). .. Cytochrome c was detected with a mouse monoclonal antibody (556433, Pharmingen).



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